Alfred University Research and Archive (AURA)

Doped Bioglass Microsphere Characterization and Analysis

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dc.contributor.advisor Wren, Anthony
dc.contributor.advisor Keenan, Timothy
dc.contributor.advisor Griffith, Abigail Smith, Amber 2020-05-19T18:21:03Z 2020-05-19T18:21:03Z 2020-05-05
dc.description Thesis completed in partial fulfillment of the requirements for the Alfred University Honors Program. en_US
dc.description.abstract The creation of 45S5 Bioglass® microspheres and doped silver (Ag), copper (Cu), nickel (Ni) and zinc (Zn) 45S5 Bioglass® microsphere were completed via a torch flame process. Characterization included optical microscopy, R statistical modeling, X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Optical microscopy allowed for color analysis and particle size measurements, specifically diameter, to be collected on the microspheres. This data was evaluated using R t-testing which determined that based on p-value dopants significantly effected microsphere size. Similarly, visual displays were created using R to support the statistics within a sample. XRD showed an amorphous sample with crystalline peaks. These peaks were aligned with the dopant of each glass. Shape, and surface assessment of the microspheres was examined using SEM. From the SEM images, the surface of the microspheres are not smooth and samples contained aspherical particles, but all contained many spherical particles. This characterization indicates better process controls need to be implemented. Additionally, through EDS, maps of dopant dispersion in the microspheres was obtained. From the surface, control 45S5 Bioglass® was evenly distributed containing all parts of the 45S5 composition but the dopants were not. Ag showed one dense location while other doped microspheres had varying distributions on the surface. en_US
dc.language.iso en_US en_US
dc.relation.ispartof Herrick Library en_US
dc.rights.uri en_US
dc.subject Honors thesis en_US
dc.subject Biomaterials en_US
dc.subject Biomaterials engineering en_US
dc.subject Biomaterials science en_US
dc.subject Bioglass en_US
dc.subject Antibacterial properties en_US
dc.title Doped Bioglass Microsphere Characterization and Analysis en_US
dc.type Thesis en_US

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