Investigation of Swelling and Antibacterial Properties of Hydrogel Composites Containing 45S5 Bioactive Glass

Simple Item Record
dc.contributor.advisorKeenan, Timothy
dc.contributor.advisorMcGowan, Garrett
dc.contributor.advisorWren, Anthony
dc.contributor.authorRaeman, Sarah
dc.date.accessioned2021-06-30T20:01:46Z
dc.date.available2021-06-30T20:01:46Z
dc.date.issued2021-05
dc.descriptionThesis completed in partial fulfillment of the requirements for the Alfred University Honors Program.en_US
dc.description.abstractThe properties of 5 different compositions of hydrogels were investigated to determine the potential for future medical applications. Each batch consisted of an aqueous agent, which was water, a primary polymer, a secondary polymer, and an additive, which was 45S5 bioglass. The primary polymers used were either gelatin or polyvinyl alcohol (PVA) and the secondary polymers used were cellulose gum or anhydrous borax. The first of two tests used to investigate the properties of the hydrogels was swelling studies. Samples from each batch were placed in phosphate buffered saline (PBS) and left to incubate overnight. After 24 hours, the samples were observed and batches 1 and 2 had noticeable swelling while samples from batches 3, 4, and 5 had dissolved. The following day observations were made again and batches 1 and 2 had started to dissolve as well. Bacterial testing was then conducted with 3 samples for each batch being placed in LB agar and tested against Escherichia coli (E. coli). Batches 3, 4, and 5 all had varying sizes of inhibition zones and batches 1 and 2 showed no signs of inhibition of bacterial growth. Batches 3, 4, and 5 all had anhydrous borax as the secondary polymer while batches 1 and 2 had cellulose gum.en_US
dc.identifier.urihttp://hdl.handle.net/10829/24529
dc.language.isoen_USen_US
dc.relation.ispartofHerrick Libraryen_US
dc.rights.urihttps://libraries.alfred.edu/AURA/termsofuseen_US
dc.subjectHonors thesisen_US
dc.subjectHydrogelsen_US
dc.subjectBioglassen_US
dc.subjectPolymersen_US
dc.titleInvestigation of Swelling and Antibacterial Properties of Hydrogel Composites Containing 45S5 Bioactive Glassen_US
dc.typeThesisen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Raeman, Sarah 2021.pdf
Size:
1.32 MB
Format:
Adobe Portable Document Format
Description:
Thesis
Download

Collections

Student Honors Theses